摘要
Tendon tissue engineering is one of the research fields with longhistory, which has achieved dramatic advances This paper reviewed some recent original articles, mainly in sources of seeding cells of tendon tissue engineering, the level of immunological reaction with allogeneic tendon cells, preparation and screening of scaffold materials with specific mechanical and degenerating properties, the interaction of cells, scaffold materials, and so on To establish the standard tendon cell line for research has significance in the study of the biological characteristics of tendon cells, the cell model for immortalization, and screening the various scaffold materials The immunological reaction of the tissue engineered tendon with allogeneic cells in the research and future clinical applications must be clarified It is requested by tissue engineering research that the scaffold materials with specific mechanical and degenerating properties and the three dimensional culture technique mimic microenviroment in vivo, including the mechnical stress and strain All of those should be extensivly studied to lay a solid foundation for ultimate clinical
Tendon tissue engineering is one of the research fields with longhistory, which has achieved dramatic advances This paper reviewed some recent original articles, mainly in sources of seeding cells of tendon tissue engineering, the level of immunological reaction with allogeneic tendon cells, preparation and screening of scaffold materials with specific mechanical and degenerating properties, the interaction of cells, scaffold materials, and so on To establish the standard tendon cell line for research has significance in the study of the biological characteristics of tendon cells, the cell model for immortalization, and screening the various scaffold materials The immunological reaction of the tissue engineered tendon with allogeneic cells in the research and future clinical applications must be clarified It is requested by tissue engineering research that the scaffold materials with specific mechanical and degenerating properties and the three dimensional culture technique mimic microenviroment in vivo, including the mechnical stress and strain All of those should be extensivly studied to lay a solid foundation for ultimate clinical applications
出处
《基础医学与临床》
CSCD
北大核心
2001年第6期497-500,共4页
Basic and Clinical Medicine
基金
国家科技部"973"项目 (G19990 5 430 8)
国家自然科学基金 (39830 10 0 )
美国纽约中华医学基金
四川省卫生厅及科技厅项目
关键词
组织工程肌腱
种子细胞
支架材料
tendon cells
scaffold materials
repair
tissue engineering
