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经犬胰十二指肠前动脉注射尿素溶液后的病理观察

The pathology change with 40 percent urea solution though the anteior artery of pacreaticodudenum
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摘要 目的 讨论药物缺血治疗胰癌的可行性。方法 解剖犬胰腺、胰十二指肠前动脉 ,结扎近心端后 ,远心端置入化疗泵 ,术中、术后从化疗泵中注射尿素溶液 (2 0 mg/kg体重 ,浓度 40 % ) ,分别于术后观察胰腺及十二指肠病理变化 ,观察动物生存情况。结果 实验用犬在实验期内均生存良好 ,胰腺病理变化为严重纤维化表现 ,十二指肠病理改变较轻。 Objective To explore the possiblity of medicine ischemic treatment to pancreatic carcinoma Methods The dog's pancrease and anterior artery of pancreaticoduodem were dissected,the approximal artery was ligated and a chematherapy pump was inserted into the distal artery Both during and after the operation,urea selution was injected(20mg/kg,40%in Concentration) After the operation,special attention was paid to the pathological of pancrease and duodenum and alive state of doges Results The experiment doges were all alive well in experiment period ,the pancreatic pathology was serious fiberies and the duodenum change was only atrphied slighthy Conclasion Medicine ischemic treatment to pancrease is possibllity
出处 《医学文选》 2001年第5期591-593,共3页 Anthology of Medicine
关键词 胰十二指肠前动脉 尿素溶液 胰腺病理 十二指肠 病理 The anterior pancreaticoduodenal artery urea Solution Pancreatic pathlolgy Duodenum pathology
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  • 1[1]Bakkevold KE, Kambestad B. Palliation of pancreatic can cer. A prospective multicentre study [J]. EurJ Surg Oncol, 1995,21(2): 176
  • 2[2]Nederhuber JE, Breaman MF, Menck H. The national cancer date base report on pancreatic cancer [J]. Cancer, 1995,76(9)1671
  • 3[3]Walsh D. Palliative management of the patient with ad vanced pancreatic cancer [J]. Oncol Huntingt, 1996, (9 suppl):40
  • 4李荣.医疗用金属纤维[J]日本医学介绍,1994(03).

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