摘要
目的 提高中晚期胰头癌的姑息性治疗效果。 方法 对２６ 例中晚期胰头癌患者施行了胆肠吻合术，手术中行直线加速器肿瘤区直接照射，同时手术中经胃十二指肠动脉置入埋入式化疗泵，手术后行肿瘤区灌注化疗。 结果 随访３ ～２７ 个月，全疗程结束后肿块均有不同程度缩小，疼痛缓解率为１００ ％ 。６ 个月生存率为１００ ％ ，１２ 个月生存率９３９ ％ ，２４ 个月生存率２０ ％ 。死亡的５例，平均生存期为１７８ 个月。 结论 内引流并术中放疗和灌注化疗是延长中晚期胰头癌患者生命的有效方法。
Objective To improve the palliative effect on intermediate or advanced pancreatic head carcinoma. Methods 26 patients with intermediate or advanced pancreatic head carcinoma underwent cholecystojejunostomy combined with intraoperative radiotherapy with an electron beam on carcinoma from May 1996 to May 1998. The catheter of multifunctional implantable drug delivery system was inserted via gastroduodenal artery for postoperative perfusion chemotherapy. Results Follow up for 3～27 months showed that all carcinomas shrinked with pain released in different degrees after a course of treatment. The 6 month, 12 month and 24 month survival rates were 100%, 93 9% and 20% respectively. Five patients survived on the average for 17.8 months. Conclusions This protocol is effective to prolong the life of the patients with intermediate or advanced pancreatic head carcinoma.
出处
《中华外科杂志》
CAS
CSCD
北大核心
1999年第8期472-474,共3页
Chinese Journal of Surgery
