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基因修饰细胞介导的肿瘤治疗 被引量：1

Tumor therapy mediated via gene-modulated cell vaccine
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摘要 肿瘤的基因治疗 ,最终都是通过基因修饰细胞介导完成的。这些基因修饰细胞可分为①免疫基因修饰的肿瘤细胞疫苗 ;②自杀基因或抑癌基因修饰的细胞疫苗 ;③基因修饰的树突状细胞 (DC)疫苗 ;④基因修饰造血干细胞 ;⑤基因修饰淋巴细胞 ;⑥基因修饰血管内皮细胞及其它。它们在肿瘤的基因治疗中各有特点 ,本文主要介绍这些方面的研究进展。 Tumor genetherapy is carried out finally mediated by gene modulated tumor cells. Vaccines made of modulated cells are:①immune gene modulated tumor cells;②suicide gene or tumor suppress gene transfected cells;③exotic gene induced dentritic cells;④modulated hemopoietic stem cell;⑤exotic gene modulated lymphocytes;⑥gene modulated vascular endothelial cells, etc. These modulated cells have their own specificity, this review introduce the progress of study on this respect.
作者 王澜 吴祖泽
机构地区 军事医学科学院放射医学研究所
出处 《生物技术通讯》 CAS 2001年第4期275-278,共4页 Letters in Biotechnology
关键词 肿瘤 基因治疗 基因修饰细胞 肿瘤疫苗 介导 tumor genetherapy, gene modulated cell, tumor vaccine
分类号 R730.51 [医药卫生—肿瘤]
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参考文献26

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共引文献22

同被引文献27

  • 1白春学,张新.肺癌的治疗现状[J].中华结核和呼吸杂志,2006,29(3):146-148. 被引量：61
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引证文献1

生物技术通讯
2001年 第4期

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