摘要
目的 :探讨病毒性心肌炎 (VMC)中西药物合治的疗效。方法 :治疗组 (6 6例 )选用黄芪注射液、辅酶Q1 0 和维生素 C(V it C) ;对照组 (5 0例 )选用 GIK极化液、辅酶 Q1 0 和 Vit C;两组患者无禁忌证者均给予 β-受体阻滞剂、钙拮抗剂和对症治疗 ,观察治疗前及治疗后 3个月动态心电图、超声心动图、肌酸激酶、肌钙蛋白 T、柯萨奇病毒 B Ig M、抗心肌线粒体 ADP/ATP载体抗体、肠病毒 RNA的变化。结果 :治疗组与对照组治疗后比较 ,心律失常减少 (P <0 .0 1) ,左室舒张末内径缩小 (P <0 .0 5 ) ,肌酸激酶明显下降 (P <0 .0 1) ;治疗组治疗前后比较 ,左室射血分数增加 (P <0 .0 1) ,抗心肌线粒体 ADP/ATP载体抗体阳性率降低 (P <0 .0 5 )。结论 :采用中西药物合治方案是治疗 VMC有效途径之一。
Objective:To study the effectc of combined treatment of traditional Chinese medicine with Western medicine on vi ral myocarditis. Method:One hundred and sixteen patients with viral myocard itis who were collected from 1996 to 1999 were divided randomly and monoblindly into two groups: ① treatment group, including 66 cases treated with huangqi, c oenzyme Q 10 and vitamin C; ② control group, including 50 cases treated wi th GIK, coenzyme Q 10 and vitamin C. For both groups, β-blocker, calcium antagonist and conventional therapies were added if no contraindication existed. The observed indices included Holter test, UCG, CK, cTnT, CoxB-IgM, AHA and EV s-RNA. Result:Compared with treatment group, control group had higher morbidity of arrhythmia (P< 0.01), LVEDd (P< 0.05) and CK (P< 0.01) . Furthermore, in treatment group, LVEF was significantly incre ased (P< 0.01) and the positive rate of AHA was reduced (P< 0.05) after treatment.Conclusion:According to the characteristics of huangqi, co enzyme Q 10, vitamin C , β-blocker and calcium antagonist, we can treat v iral myocarditis effectively by using combined treatment of traditional Chinese medicine with Western medicine.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
2001年第8期353-355,共3页
Journal of Clinical Cardiology
基金
国家"95"医学攻关科技项目 (No.96 90 6 0 2 13)
关键词
病毒性心肌炎
中西医结合治疗
VMC
疗效
Viral myocarditis
Integrated traditional chine se and Western medicine
