摘要
为研究中药双龙丸治疗冠心病的机理 ,将 64例冠心病患者以单盲法随机分为治疗组和对照组 ,分别给予中药双龙丸、西药开博通合长效异乐定治疗 ,疗程为 1～ 3M ,观察治疗前后心肌缺血总负荷 (TIB)、一氧化氮(NO)、内皮素 (ET)、血管紧张素Ⅱ (AngⅡ )、颈动脉内中膜 (IMI)及颈动脉斑块厚度、面积的变化。结果 :治疗组TIB、ET、AngⅡ降低 ;NO升高 ;IMI、颈动脉斑块与面积缩小 ,与治疗前比较均有显著性差异 ;与对照组比较 ,ET、NO、IMI和斑块厚度 ,治疗后有显著差异。提示双龙丸有抗动脉粥样硬化和血管内皮保护的作用 。
To investigate the mechanism of 'Shuanglong Pill',a Chinese patent medicine,64 subjects with coronary heart disease were classified with single blindness method into treatment group and control group,and then were treated with'Shuanglong Pill'and kaibotong plus longacting yileding respectively for 1～3 months.The total ischemia load(TIB),NO,ET,angiotensin Ⅱ(AngⅡ),IMI and the thickness and area of arteria carotis plaque were observed.Results showed dropped TIB,ET and Ang Ⅱ,elevated NO and reduced IMI and plaque,with a striking difference between pre treatment and post treatment,indicating that'Shuanglong Pill'can relieve myocardial ischemia.
出处
《上海中医药杂志》
北大核心
2001年第7期14-15,共2页
Shanghai Journal of Traditional Chinese Medicine
