摘要
目的 观察山莨菪碱 (6 5 4 2 )对油酸致急性肺损伤的作用。方法 测量家兔血清中丙二醛 (MDA)的含量 ,及支气管肺泡灌洗液 (BALF)中MDA、蛋白含量和肺湿 /干重比。结果 6 5 4 2可明显减少油酸性急性肺损伤家兔血清及BALF中MDA和BALF中蛋白含量 ,并使肺湿 /干重比降低。结论 6 5 4 2可通过其抗膜脂质过氧化对油酸性肺损伤起到有效的防治作用。
Objective To observe the effect of anisodamine when the lung was injuried by oleic acid.Methords Measurement was made of malondialdehyde(MDA) content in rabbit's serum and MDA, and protein content in broncho-alveolar lavage fluid (BALF) and wet-to-dry weight ratio of the lung .Results 654-2 reduced the MDA content in rabbit's serum and in BALF, protein content in BALF and wet-to-dry weight ratio of the lung. Conclusion 654-2 may to some extent prevent the lung from being injuried by oleic acid or may reduce the possibility through the anti-peroxidation of lipid membrane.
出处
《皖南医学院学报》
CAS
2001年第3期168-168,171,共2页
Journal of Wannan Medical College
