摘要
目的 本实验应用功能磁共振成像 (fMRI)的回波平面 (EPI)技术 ,着重研究了人脑视皮质的血氧水平依赖 (BOLD)的功能磁共振成像。方法 本实验包括对 36名正常健康志愿者及 17例具有枕区病变患者的fMRI研究。在刺激和静止 2种对比条件下采集枕区的回波平面图像。结果 主要视皮质位于双侧距状裂两侧 ,属于布劳德曼 (Brodmann) 17区。 3例具有距状裂附近病变的患者的视皮质由于病变的占位效应而发生移位。结论 fMRI可用于在活体人脑上研究各功能区活动。视觉刺激下的fMRI可对人脑视皮质初步定位。由于病变占位效应的影响 ,病变周围的功能活动区常发生变形或移位。
Objective This test is focused on functional magnetic resonance imaging(fMRI) of visual cortex by using echo planar imaging(EPI) and blood oxygenation level dependent(BOLD) contrast. Methods 36 normal volunteers and 17 patients with lesions at occipital lobe were included in this test. The echo planar images of the occipital area were acquired at visual stimulation and rest phases. Results The primary visual cortex was located at the bilateral calcarine cortex, which belonged to Brodmann area 17. The functional areas showed displacement due to the mass effect of lesions near calcarine cortex in 3 patients. Conclusion fMRI can be used to study human functional cortex. A preliminary location of visual cortex can be acquired through visual stimulation. The invasion of the intracranial massive lesions to functional areas the disappearance of functional activation. The mass effect of intracranial lesions may lead to deformation or displacement of the near functional areas.
出处
《中华放射学杂志》
CAS
CSCD
北大核心
2001年第7期524-527,共4页
Chinese Journal of Radiology
关键词
磁共振成像
视皮质
光刺激
回波平面成像
临床应用
脑
Magnetic resonance imaging
Visual cortex
Photic stimulation
Echo planar imaging
