摘要
目的 :探讨小儿中枢神经系统感染时白介素 8(IL 8)、粒细胞集落刺激因子 (G CSF)的变化。方法 :用ELISA法检测 91例中枢神经系统感染患儿中的 5 9例病毒性脑炎或脑膜脑炎 (Vm&Ve)患儿、2 2例化脓性脑膜炎患儿 (Pm)和 10例结核性脑膜炎患儿 (Tm) ,并以 2 1例非神经系统疾病患儿的脑脊液、血清G CSF和IL 8活性作为对照。结果 :患儿组脑脊液IL 8明显高于对照组 (P <0 .0 5 ) ,但患儿组间差异无显著性。G CSF各组间差异无显著性。结论 :IL 8在中枢神经系统感染发病中起作用 ,但IL 8、G CSF的检测无鉴别诊断价值。
Objective:To explore the significance of cerebrospinal fluid of IL 8,G CSF in children with central nervous system infection.Methods:IL 8,G CSF concentrations of cerebrospinal and serum were measured by ELISA in 59 patients with viral meningitis or encephalomeningitis, 22 patients with bacterial meningitis, 10 patients with tuberculous meningitis and 21 children with no central nervous system infection as the control.Results:IL 8 concentration of patients were significantly higher than the control(P<0.05),but between the patient's groups no differences was found.Conclusions:IL 8 plays a role in the inflammatory process of central nervous system infection,but it is not of much value in differential diagnosis.
出处
《温州医学院学报》
CAS
2001年第2期81-82,共2页
Journal of Wenzhou Medical College
基金
浙江省教育委员会课题! ( 942 11)
