摘要
【目的】观察针药结合疗法对免疫性不育大鼠模型血清抗精子抗体的影响。【方法】将 80只SD大鼠分为 4组 ,采用主动免疫法建立血清抗精子抗体 (ASAb)阳性大鼠模型 ,并于造模时同期分别用针刺 (取穴关元俞、次 )、归肾液 (由熟地、菟丝子、女贞子、淮山、枸杞子、桑寄生、山萸肉等组成 )及针药结合治疗。【结果】针刺结合归肾液治疗组SD大鼠血清ASAb阴性率明显高于归肾液、针刺治疗组 (P <0 .0 5及P <0 .0 1)。【结论】说明针药结合有抑制ASAb产生的作用。
Objective To explore the effect of acupuncture combined with Guishen Decoction (GD) on serum antisperm antibody (ASAb) level of rat models with immunological infertility. Methods Active immunization was used to establish rat models with positive serum ASAb. Eighty SD rats were alloc ated to four group s: Group A (treated with acupuncture and GD), Group B( treated with GD), Group C (treated with acupuncture), Group D (model control group). GD is composed of Ra dix Re hmanniae Praeparata, Semen Cuscutae, Fructus Ligustri Lucidi, Rhizoma Dioscorae, Fructus Lycii, Ramulus Loranthi, etc.. Results The negative rate of serum A SAb in Group A was significant higher than that in Group B and Group C (P< 0.05 ,P< 0.01 respectively). Conclusion Acupunctur e combined with GD exerts a certain effect in inhibiting the formation of serum ASAb.
出处
《广州中医药大学学报》
CAS
2001年第2期140-143,共4页
Journal of Guangzhou University of Traditional Chinese Medicine
基金
卫生部立项课题!(编号 :98- 1- 10 7)
关键词
免疫性不育
针灸疗法
中医药疗法
抗精子抗体
归肾液
INFERTILITY/ TCD therapy
INFERTILITY/ acu_mox therap y
GUISHEN DECOCTION/ther. use
ANTISPERM ANTIBODY
KIDNEY-REINFORCING DRUGS/ther.use
POINT BL26
POINT BL32
DISEASE MODELS, ANIMAL
RATS
