摘要
【目的】从微观病理探讨穴位敷贴治疗哮喘的机制。【方法】采用随机对照的研究方案 ,以自制敷贴方敷贴实验性哮喘模型颈背“穴位”。敷贴方由麻黄、细辛、甘遂、延胡、附片、防风、五味子、白芥子组成。【结果】从第 6天开始 ,贴药组点头呼吸的潜伏时间明显延长 ,与哮喘组比较差异有显著性 (P <0 .0 5) ;从第 9天始穴位敷贴组豚鼠发生点头呼吸的频度明显减少 ,与哮喘组比较差异有显著性 (P <0 .0 1) ;且贴药组有降低豚鼠炎性渗出及嗜酸性粒细胞数的作用 (与哮喘组比均P <0 .0 5)。【结论】提示穴位敷贴治疗哮喘可能是通过延长哮喘发作的潜伏期 ,减小哮喘发作的频度 ,减少肺组织水肿、渗出 ,降低嗜酸性粒细胞的肺系局部浸润而实现的。
Objective To investigate the microcosmic pathologic mechanism of ac upoint application for asthma. Methods Sixty guinea pigs were randomly alloca ted to three groups: Group A (model control), Group B (guinea pig model treated with acupoint application) and Group C (normal control). Group B was treated wit h the application of herbal medicines on the acupoints located at neck and back. Results From the 6th day of treatment, incubation period of nodding breath was prolonged in Group B as compared with Group A (P< 0.05 ). And from the 9th day, the frequency of nodding breath was lowered (P< 0.01 ). Inflammatory exudation and eos inophil number were decreased in Group B as compared with Group A (P< 0.05 ). Conclusion The mechanism o f acupoint application for asthma is probably related to the prolongation of incubation period and the decrease of frequency of asthma a ttack, and the reduction of inflammatory exudation and infiltration in lung tiss ue.
出处
《广州中医药大学学报》
CAS
2001年第2期137-139,共3页
Journal of Guangzhou University of Traditional Chinese Medicine
关键词
哮喘
穴位疗法
穴位贴敷法
疾病模型
病理
ASTHMA/acupoint therapy
ACUPOINT STICKING THERAPY
FACILITATING LUNG/ther. use
DISEASE MODELS, ANIMAL
GUINEA PIGS
