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输精管绝育术后经皮穿刺吸精子IUI辅助授孕技术临床研究 被引量:2

Study of Restorative Fertility of Vasectomized men using percutaneous sperm aspiration via intrauterine insemination(IUI).
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摘要 应用经皮穿刺输精管吸精子(PVSA)及经皮穿刺附睾吸精子(PESA)宫腔内人工授精(IUI)技术,治疗男性绝育术后要求复育或复通复育失败者共28例。其中PVSA 16例,IUI 16个月经周期,6例妊娠,周期妊娠率37.5%;其余12例由于吻合术后输精管与周围组织粘连严重采用PESA,4例从附睾尾吸出精子,IUI后1例妊娠并足月出生一健康男婴;8例从附睾头吸出活精子,IUI 10个月经周期,1例妊娠,现已4个月。结论认为,附睾头部精子进入女性生殖道内具有自然受精能力;PESA或PVSA结合IUI治疗男性绝育术后要求复育者安全、经济、有效,其辅助授孕技术为男性绝育术后复育提供了新的途径。 Objective:To restore fertility of vasectomized men using percutaneous epididymal sperm aspiration (PESA) and percutaneous vasal sperm aspiration (PVSA) via intrauterine insemination (IUI). Patients :Twenty-eight vasectomized men who required restoration of their fertility with PESA,PVSA and IUI. Main Outcome Measure:Clinical Pregnancy. Results:Of 28 vasectomy reversal subjects, 16 cycles of IUI using vasal sperm by percutanoues aspiration were performed in 16 subjects and 6 pregnancies were achieved. 14 IUIs with epididymal sperm by percutanoues aspiration were carried out in 12 subjects with epididymal obstruction due to vasovasotomy for vasectomy reversal,and 2 pregnancies were achieved using caudal and caput epididymal sperm by percutanoues aspiration respectively. Conclusion : The PESA-IUI and the PVSA-IUI techniques are attractive, economical and utility for vasectomy reversal. The pregnancy by IUI using PESA and PVSA reveals that the caput epididymal sperm possesses fertilization capacity in female reproductive tract and provides a new approach for the restorative fertility of vasectomized men.
出处 《中国计划生育学杂志》 2001年第3期174-175,181,共3页 Chinese Journal of Family Planning
基金 山东省计划生育委员会资助项目
关键词 PVSA PESA IUI 输精管结扎 复育 Vasectomy reversal Percutaneous epididymal sperm aspiration (PESA) IUI Caput epididymal sperm Percutaneous vasal sperm aspiration(PVSA)
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