摘要
为探讨卵浆内单精子显微注射(ICSI)及经皮穿刺附睾吸取精子(PESA)治疗严重少、弱、畸形精子及精道不通男性不育患者的价值,对7对男性不育夫妇采用ICSI或PESA+ICSI治疗。对女方常规促超排卵、取卵,共获卵子97个,其中成熟卵子81个,行ICSI后存活72个,受精率为62.5％,每周期可移植胚胎2～4个,临床妊娠6例。于1998年2月16日足月出生一正常男婴(PESA+ICSI)。初步研究表明:ICSI或PESA+ICSI技术是治疗男性因素不育的有效方法,尤其PESA+ICSI技术为男性输精管绝育(结扎、粘堵)受术者提供生殖保险。
Our purpose was to study whether micromanipulation using Intracytoplasmic sperm injection (ICSI) or Combined percutaneous epididymal sperm aspiration (PESA) and ICSI could improve the poor fertilization and pregnancy rates obtained when attempling in vitro fertilization in patients with severe aligo as theno teratospermia or congenital absence of the vas deferens and unreconstroctable obstructive azoospermia.ICSI and PESA - ICSI were earried in 7 treatment cycles. Nonnal fertilization and cleavage occurred in 45 of 72 oiocytes which were survived. Fertilization rate was 62. 5%, clinical pregnancy rate was 6/7. The first PESA -ICSI baby was delivered on February 16, 1998.Conclusion: ICSI or PESA- ICSI procedure is highly effective for male inferlile. Especially, the PESA - ICSI provides reproductive insurance for male sterilization operation of vas deferens (ligation or occulsion).
出处
《中国计划生育学杂志》
1998年第8期350-351,355,共3页
Chinese Journal of Family Planning
基金
山东省科学技术委员会计划项目
关键词
男性不育
ICSI
PESA
治疗
Intracytoplasmic Sperm Injection Male infertile Perentaneous epididynlal sperm aspiration
