摘要
测定了实验系统下固定化酶的本征动力学常数 ,从动力学角度分析研究了所开发研制的动态膜分离式固定化酶反应器 (DMIR)的反应过程 ,给出了无外扩散限制条件下的 DMIR反应器的数学模型 。
A Dynamic membrane-separation immobilized enzyme reactor(DMIR) was developed to apply in different operation processes successively. It is a type of continuous biological reactor which combines the immobilization of enzymes with membrane separation and which makes reaction and separation carry out simultaneously. To analyze and study the process of reaction-diffusion on the developing equipment, the kinetic parameters in various enzyme reaction systems and the intrinsic kinetic parameters of both free and immobilized glucoamylases were experimentally obtained. The experimental results showed that the rotating beds in the DMIR is superior to fixed bed as the presence of centrifugal field effectively enhances the conversion and production capacity, and in addition, it reduces or even eliminates the extra diffusion limitation. It was resulted in a increase in the reaction rate of the immobilized enzyme. The theoretical and experimental effective coefficients of different substance concentrations were calcul ated. A mathematics model of DMIR was provided without the condition of extra-diffusion limitation. Results have confirmed the reliability of the experimental method proposed in the thesis.
出处
《化学反应工程与工艺》
EI
CAS
CSCD
北大核心
2001年第2期138-142,共5页
Chemical Reaction Engineering and Technology
基金
天津市自然科学基金! (934 0 0 80 )
青年科学基金! (94130 810 )资助项目
