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深圳市人群庚型肝炎病毒感染状况调查

A study on hepatitis G virius(HGV)infection in general population of Shenzhen
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摘要 目的 探讨深圳市一般人群中庚型肝炎病毒 (HGV)感染情况及其影响因素。 方法 随机抽取研究对象 ,用酶联免疫反应法 (ELISA)检测该人群中抗 -HGV ,对阳性者用逆转录PCR(RT -PCR)检测血清中HGVRNA。 结果 抗 -HGV阳性率为 9 33%。男女分别为 9 5 1%和 9 13% ;HGVRNA阳性率为 2 33% ,男女分别为 2 45 %和 2 2 0 % ,年龄组间抗 -HGV和HGVRNA阳性率差异均无显著性 ;单因素和logistic回归分析未显示肝炎病史、近期手术史、注射史、拔牙史及乙型肝炎疫苗接种史等因素与HGV感染有关 ;职业人员中以中学生及教师的HGVRNA阳性率较高。 结论 深圳市一般人群中HGV感染率较高 ,但其流行因素尚待进一步研究。 Objective To explore the prevalence of hepatitis G virus(HGV)infection and its risk factors among the general population in Shenzhen Methods According to the culster sampling,1843 subjects were selected randomly and tested for anti-HGV in sera by ELISA; And the samples which the anti-HGV were positive were further tested for HGV RNA using RT-PCR. Results The prevalence rate of anti-HGV was 9.33% in the population, The prevalence of HGV RNA was 2.33% (2.45% for male and 2.20% for female,respectively).There was no significant difference between different age groups.The histories of hepatitis, surgical、 dental operations and injections were associated with HGV infection.However,It was higher in middle school students and teachers. Conclusion The prevalence of HGV RNA seemed to be high among the general population in Shenzhen,The risk factors of HGV infection in the population needed to be further studied.
出处 《实用预防医学》 CAS 2001年第3期183-185,共3页 Practical Preventive Medicine
关键词 庚型肝炎病毒 酶联免疫反应法 逆转录聚合酶链反应法 流行病学 Hepatitis G virus ELISA RT-PCR Epidemiology
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