摘要
测量50例口腔颌面部鳞癌患者临床肿瘤厚度和59例患者病理肿瘤厚度及区域淋巴结有否转移,利用 ROC 曲线评价发现,患者临床肿瘤厚度和病理肿瘤厚度的阈值分别为12mm和5mm,当患者肿瘤厚度大于阈值时,其发生区域淋巴结转移的概率明显增加,对这些患者均应施行同期颈淋巴结清扫术。本文的结果还表明:临床肿瘤厚度和病理肿瘤厚度之间有正相关关系,而肿瘤表面最大直径和肿瘤厚度之间无相关关系。
Tumor thickness has been found to be very useful in determining the prognosis in pa- tients with cancer.To shed light on the value of measuring thickness,59 oral squamouscancers were analyzed to find the degree of correlation between greatest thickness measur-ement and pathologic nodal spread.With metastasis has a mean clinical tumor thicknessfor 18.4mm,a mean pathologic tumor thickness for 7.4mm;Without metastasis has a meanclinical tumor thickness for 9.9mm,a mean pathologic tumor thickness for 4.5mm.Therehas significance(P<0.05).According to ROC curve,the authors suggested that 12mm forclinical thickness and 5mm for pathologic tumor thickness is a cut-off point for lymph no-de metastasis.In any case,neck dissection seems appropriate for the oral cancer patientswhose clinical tumor thickness exceed 12mm or pathologic tumor thickness exceed 5mm,asthe risk of cervical lymph nodes metastasis in such patients approached 44～51.7 percentin the study.
出处
《华西口腔医学杂志》
CAS
CSCD
北大核心
1991年第4期299-302,共4页
West China Journal of Stomatology
基金
国家自然科学基金
