摘要
目的 观察立体定向放射手术治疗脑转移瘤的疗效。方法 X线立体定向放射治疗脑转移瘤患者 47例 ,采用 10MV的直线加速器多个非共面弧旋转照射 ,肿瘤剂量为 18～ 2 5Gy(平均 2 2 .1Gy)。 40例患者在术后接受了肿瘤剂量 30～ 40Gy的全脑放疗。结果 中位生存期为 11个月 ,1年生存率 37.5 % ,疗后 3个月的肿瘤控制率为 90 .7% ,KPS≥ 70、原发肿瘤已控和无颅外转移患者的预后较好 (P <0 .0 5 )。
Objective To evaluate the effectiveness of X ray stereotactic radiosurgery (SRS) for brain metastases.Methods Retrospective analysis of 47 patients with brain metastases who underwent SRS under a 10 MV linear accelerator was carried out.Tumor diameter varied from 12 mm t o 40 mm (mean 27mm ).Tumor dose varied from 18～25Gy (mean 22.1Gy).Fractionated whole brain radiotherapy was delivered to 40 patients after SRS.32 patients were examined by CT and (or) MRI.Results Median survival from SRS was 11 months.Tumor control rate was 90.7% after SRS.Tumor complete response rate was 68.8%.Tumor recurrence was found by CT or MRI.There was longer survival in KPS≥70,primary tumor was controlled and no extracranial metastases was found.The main complication was brain edema(18.8%).Conclusion The results of this report shows that SRS is an effective and safe treatment option.
出处
《中国肿瘤临床与康复》
2001年第2期72-73,共2页
Chinese Journal of Clinical Oncology and Rehabilitation
