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丝裂霉素C在泪囊鼻腔吻合术中的应用 被引量:9

Application of mitomycin C to dacryocystorhino-stomy
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摘要 目的 探讨丝裂霉素 C在泪囊鼻腔吻合术中的应用及效果。方法 将 92例 10 5眼慢性泪囊炎随机分为 MMC组 48例 5 5眼和对照组 44例 5 0眼 ,MMC组术中应用 0 .4g· L- 1 MMC,对照组未用 MMC,术后平均随访 2 9m o。结果 手术成功率 :MMC组为98.0 8% ,对照组为 82 .6 1% (P<0 .0 5 )。吻合口开通率 :MMC组为 10 0 % ,对照组为82 .6 1% (P<0 .0 1)。前后瓣膜愈合时间 :MMC组为 7.86 d± 2 .75 d,对照组为 7.2 2 d±2 .2 3d(P>0 .0 5 )。吻合口出血发生率 :MMC组为 3.6 2 % ,对照组为 2 % .结论  MMC可作为治疗慢性泪囊炎的一种安全、简单、有效的辅助措施 。 Objective To probeinto the application and effect of mitomycin C(MMC) to dacryocystorhinostomy Methods The chronic dacryocystisis,92 cases(105 eyes)were performed with the same level dacryocystorhinostomy,randomly divided into two groups:MMC group,48 cases(55 eyes) given MMC 0 4g·L -1 Control group,44 cases (50 eyes) without MMC The average period of postoperative following up was 29 months ResultsThe successful rates of remote operations: 98 08% in MMC group,82 61%( P <0 05) in the control group The percentage of anastomotic stoma open:100% in MMC group,82 61%( P <0 01) in the control group Healing period of anterior and posterior valve:7 86d±2 75 d in MMC group and 7 22d±2 23d( P >0 05) in the control group The bleeding ratio of anastomotic stoma:3.62% in MMC group, 2% in the control group.Conclusion MMC can be used as one of safe ,simple ,effective and auxiliary measures to treat chronic dacrocystisis,which can notably enhance the successful rates of operations
出处 《眼科新进展》 CAS 2001年第2期107-108,共2页 Recent Advances in Ophthalmology
关键词 丝裂霉素C 慢性泪囊炎 泪囊鼻腔吻合术 mitomycin C chronic dacryocystisis dacryocystorhinostomy
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参考文献4

  • 1[1]Kao SC,Liao CL,Tseng JH,et al.Dacryocystorhinostomy with intraoperative mitomycin C[J].Ophthalmology 1997;104(1)∶86-91.
  • 2[2]Ugurbas SH,Zilelioglu G,Sargon MF,et al.Histopathologic effects of mitomycin C on endoscopic transnasal dacryocystorhinostomy [J].Ophthalmic Surg Lasers 1997;28(4)∶300-304.
  • 3[3]Yeatts RP,Neves RB.Use of mitomycin C in repeat dacryocystorhinostomy [J].Ophthal Plast Reconstr Surg 1999;15(1)∶19-22.
  • 4[4]Woo KI,Moon SH,Kim YD.Transcanalicular laser assisted revision of failed dacryocystorhinostomy[J]. Ophthalmic Surg Lasers 1998;29(6)∶451-455.

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