摘要
目的:为了探索泪道阻塞与遗传的关系,以便今后能从遗传学方面提供预防和治疗措施作参考。方法:1980-08/2004-08随机调查了来院门诊和住院患泪道阻塞的患者及家系中患泪道疾病的情况,分别绘制家系图。结果:调查了340个家系3292人,发病512人,占15.6%。一级亲2879人,占家系人口的87.5%,发病467人,占一级亲的16.2%;二级亲385人,占家系人口的11.7%,发病45人,占二级亲的11.7%;三级亲28人,占0.8%,无发病。结论:泪道阻塞属于遗传性疾病,其遗传方式:①常染色体显性;②常染色体隐性;③散发。
AIM： To explore the relationship between lacrimal duct occlusion and genetics, so as to offer references for further treatment of lacrimal duct occlusion from the perspective of genetics in the future.
METHODS： From August 1980 to August 2004, the lacrimal duct occlusion suffering status of the outpatients in our hospital was randomly researched, and their family trees were drawn.
RESULTS： A total of 3 292 people in 340 genealogies were investigated, among whom 512 people had lacrimal duct occlusion, with the occurrence rate of 15.0%. First degree relatives included 2 879 people （87.5%）,among whom 467 people had lacrimal duct occlusion （16.2%）; Second degree relatives included 385 people （11.7%）,among whom 45 people had lacrimal duct occlusion （11.7%）; Third degree relatives included 28 people （0.8%）, among whom no one had lacrimal duct occlusion.
CONCLUSION： Lacrimal duct occlusion is a genetic disease, and its genetic models include autosome dominant, autosome recessive and sporadic.
出处
《国际眼科杂志》
CAS
2005年第6期1279-1280,共2页
International Eye Science
关键词
泪道阻塞
遗传
研究
lacrimal duct occlusion
genetics
study
