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国际泌尿病理协会前列腺癌Gleason分级系统基本特征初步分析 被引量:24

Basic features of the ISUP prostate carcinoma Gleason grading system: A preliminary analysis
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摘要 目的:探讨国际泌尿病理协会(ISUP)前列腺癌Gleason评分(GS)系统主要特征。方法:分析667例前列腺癌GS、主要分级(PG)、次要分级(SG)以及第3种分级(TG)均值以及所占百分率。结果:前列腺癌GS、PG、SG以及TG值分别为(7.06±1.10)、(3.53±0.66)、(3.53±0.72)分以及(4.30±0.96)分。GS 5、6、7、8、9、10分分别占0.4%(3/677)、37.2%(252/677)、34.4%(233/677)、13.7%(93/677)、12.0(81/677)以及2.2%(15/677),其中GS≤6分占37.7%(255/677),而≥7分占62.3%(422/677);GS 3+3、4+3以及3+4分别占37.2%(252/677)、19.2%(130/677)以及15.2%(103/677);出现TG的病例占10.3%(70/677),其中3级占30.0%(21/70),4级占10.0%(7/70),5级占60.0%(42/70)。结论:ISUP前列腺癌Gleason分级系统中GS较高;GS≤6分所占比例较低,而GS≥7所占比例较高;对于GS中TG的认识还需要进一步提高。 Objective: To explore the basic features of the prostate carcinoma Gleason grading system of the International Society of Urological Pathology (ISUP). Methods : We analyzed the means and proportions of the Gleason score ( GS), primary grade (PG) , secondary grade (SG) and third grade (TG) of 667 cases of prostate carcinoma. Results : The means of GS, PG, SG and TG were 7.06 ± 1.10, 3.53 ±0.66, 3.53± 0.72 and 4.30± 0.96, respectively. The cases with GS 5, 6, 7, 8, 9 and 10 accounted for 0.4% (3/677), 37.2% (252/677), 34.4% (233/677), 13.7% (93/677), 12.0% (81/677) and 2.2% ( 15/677), respectively ; those with GS ≤6 and ≥7 constituted 37.7% (255/677) and 62.3% (422/677) ; those with GS3 + 3,4 + 3 and 3 + 4 made up 37.2% (252/677), 19.2% (130/677) and 15.2% (103/677) ; and the TG cases held 10.3% (70/677), including 30.0% ( 21/70 ) of grade 3, 10% ( 7/70 ) of grade 4 and 60.0% ( 42/70 ) of grade 5. Conclusion : Our study showed a high proportion of GS, a low proportion of GS ≤6, and a high proportion of GS ≥7 in the ISUP prostate carcinoma Gleason grading system. TG of GS needs to be further understood.
出处 《中华男科学杂志》 CAS CSCD 2014年第6期514-517,共4页 National Journal of Andrology
关键词 国际泌尿病理协会 前列腺癌 GLEASON评分 第3种分级 International Society of Urological Pathology (ISUP) prostate carcinoma Gleason score third grade
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参考文献15

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