摘要
目的:了解某院中性粒细胞缺乏肿瘤患者的抗菌药物应用情况,促进临床合理应用。方法:对该院2012年度中性粒细胞减少肿瘤患者进行回顾性调查,分析中性粒细胞缺乏患者的抗菌药物使用情况。结果与结论:患者合并感染发热的发生率为59.81%;100%的患者应用抗菌药物;依据细菌培养及药物敏感试验选择用药的占16.82%;初始治疗多采用头霉素类、第二代或第三代头孢菌素类药,或联合应用氨基糖苷类药;万古霉素未作为经验用药;补救治疗采用抗菌药物在多数情况下使用合理,但仍存在一定的不规范之处,需进一步改进。
OBJECTIVE：To analyze the antibiotic use in cancer patients with neutropenia so as to promote clinical rational use of antibiotics.METHODS：The cancer patients with neutropenia seen in our hospital in 2012 were reviewed retrospectively with regard to the antibiotic use.RESULTS ＆ CONCLUSIONS：Of all the patients reviewed,59.81％ had associated infection and fever;100％ received antibiotics; 16.82％ used antibiotics based on bacterial culture and susceptibility test; cephamycins or second-generation/third-generation of cephalosporins alone or in combination with aminoglycosides the were predominantly used as initial antibiotic regimens; vancomycin was not used as empirical therapy.The antibiotics used as remedial therapy were rational in most of the cases; however,there nonstandard antibiotic use was still noted,which thus remains to be improved further.
出处
《中国医院用药评价与分析》
2014年第4期348-350,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
