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神经母细胞瘤分子遗传学研究进展 被引量：1

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摘要 近年来儿童恶性肿瘤发病率明显上升，已成为儿童疾病主要死亡原因之一。神经母细胞瘤（neuroblastoma，NB）是常见的儿童颅外恶性肿瘤，在儿童所有肿瘤相关死亡原因中达15％。NB临床特点为原发部位隐匿，早期无特异性症状，早期诊断困难，恶性程度高，发展迅速且易发生早期转移等。NB肿瘤起源于神经嵴组织，常发生于肾上腺髓质或脊柱旁神经节，常表现为颈部、胸部、腹部和骨盆部的肿块，原发瘤最多见的部位为腹膜后和后纵隔。
作者 鲁洁 王焕民 韩炜 马晓莉 倪鑫 郭永丽
机构地区 首都医科大学附属北京儿童医院 北京儿童医院肿瘤外科 北京儿童医院血液肿瘤中心 北京儿童医院耳鼻咽喉头颈外科
出处 《中国小儿血液与肿瘤杂志》 CAS 2014年第2期65-68,共4页 Journal of China Pediatric Blood and Cancer
关键词 神经母细胞瘤 分子遗传学 颅外恶性肿瘤 主要死亡原因 儿童疾病 早期诊断 肾上腺髓质 原发部位
分类号 R739.4 [医药卫生—肿瘤]
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参考文献42

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共引文献28

同被引文献9

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中国小儿血液与肿瘤杂志
2014年 第2期

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