摘要
目的探讨广西小儿恶性实体瘤的发病特点，总结小儿恶性实体瘤的诊治经验。方法将广西医科大学第一附属医院1988年12月至2008年12月收治的323例小儿恶性实体瘤病例，按组织类型、性别、年龄、临床表现、治疗方法等进行统计分析。结果小儿恶性实体瘤中以霍奇金病（30．0％）、肾母细胞瘤（18．6％）、神经母细胞瘤（17．4％）、生殖细胞肿瘤（10．5％）最为常见；男性发病多于女性发病，男女之比为1．99：1；发病年龄呈双高峰趋势，胚胎性肿瘤多在3岁以内发病，而上皮性癌则多在10～13岁发病；患儿就诊时56．3％的主要症状为可触及的包块，极少数为体检发现；s],JL恶性实体瘤主要以中、晚期多见，Ⅲ、Ⅳ期合计占总数的64．2％；手术完整切除率为78．4％。结论D,JL恶性实体瘤的发病特点与成人肿瘤相比有很大不同；早期发现、早期诊断与早期治疗依赖早期筛查；综合治疗能有效提高手术完整切除率和改善生存质量。
Objective To explore the clinical data of the pediatric malignant solid tumor and to summarize the experiences of the pediatric malignant solid tumor treatment in Guangxi. Methods The clinical data of 323 cases of pediatric malinant solid tumor, treated surgically in the First Affiliated Hospital of Guangxi Medical University from Dec. 1988 to Dee. 2008. Pathology, sex, age, clinical characteristics, diagnosis and treatment were analysed respectively. Results The most frequent histological types were malignant lymphoma, Wilms tumor, neuroblastoma and malignant germ cell tumor. There was a male prevalence with a sex-ratio of 1.99 ： 1. The peak incidence in embryo tumor was un- der 3 years,and epithelium cancer was between the ages of 10 - 13 years. The main symptoms were palpable mass （56. 3） and a few were found in health examination;64.2% of the pediatric malignant solid tumor was of stage m or IV ; the complete tumor resection rate was 78.4%. Conclusions The characteristics of pediatric malignant solid tumor is different from those of adults. To detect as soon as possible and treat the pediatric malignant tumor as soon as possible depends on screening. Combined modality therapy can improve the patients complete resection rate and survival quality of the patients.
出处
《中华实用儿科临床杂志》
CAS
CSCD
北大核心
2013年第23期1805-1807,共3页
Chinese Journal of Applied Clinical Pediatrics
关键词
小儿恶性实体瘤
发病特点
治疗经验
Pediatric malignant solid tumor
Characteristic
Treatment experience
