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辛开苦降法治疗对脾胃病患者血清淀粉酶、血清PGE2和胃黏膜SOD活力影响研究 被引量:3

Effect of Xinkai Kujiang method on spleen and stomach disease
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摘要 目的利用辛开苦降法对脾胃病患者进行治疗,探讨脾胃病中医新应用。方法将240例脾胃病患者随机分为2组,观察组利用半夏泻心汤进行治疗,对照组口服奥美拉唑,4周后比较两组疗效、症状改善时间、血清淀粉酶水平、血清前列腺素E2(PGE2)水平和胃黏膜超氧化物歧化酶(SOD)活力变化。结果观察组有效率90.83%,对照组有效率80.83%,两组比较差异有统计学意义(P=0.000),观察组疗效优于对照;观察组反酸、胃灼热、呃逆、腹痛等症状好转和消失时间为(15.9±7.8)d,对照组为(25.4±8.9)d,两组比较差异有统计学意义(P<0.01)。治疗后,两组患者血清淀粉酶、血清PGE2水平和胃黏膜SOD活力均有好转,与治疗前比较差异有统计学意义(P<0.05);观察组各指标好转程度优于对照,差异有统计学意义(P<0.05)。结论辛开苦降法可以调节机体酶代谢,修复胃黏膜,对脾胃病疗效显著。 Objective To explore the therapy of spleen and stomach disease treated by Xinkai Kujiang method. Methods 240 cases were randomly divided into 2 groups. Observation group were treated by Banxia XiexinTang,control group were treat by oral omeprazole. The Efficacy, serum amylase and prostaglandin E2 (PGE2) levels, superoxide dismutase activity compared between two groups after 4 weeks. Results After one courses of treatment,observation group effective rate was 90.83 % ,control group effective rate was 80.83 %,the difference of two groups was statistically significant (P〈 0. 000). The time for acid reflux, heartburn, hic- cups,abdominal pain and other symptoms of observation group improved and disappear was (15.9 ±7. 8) d, control group was (25.4±8.9) d,the difference of two groups was statistically significant (P〈0.01). After treatment,the serum amylase and PGE2 levels,superoxide dismutase activity of two groups were improved. The index degree of improvement in observation group was bet- ter than the control group,the difference was statistically significant (P〈0.05). Conclusion Xinkai Kujiang method can adjust the body's metabolic enzymes,repair the gastric mucosa. The curative of spleen and stomach disease is remarkable.
出处 《国际检验医学杂志》 CAS 2014年第7期831-832,共2页 International Journal of Laboratory Medicine
关键词 辛开苦降法 脾胃病 血清淀粉酶 前列腺素E2 超氧化物歧化酶 PROSTAGLANDIN E2 Xinkai Kujiang method spleen and stomach disease serum amylase prostaglandin E2 superoxide dismutase
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