摘要
目的 :探讨唾腺粘膜相关型淋巴瘤 (MALT ML)与良性淋巴上皮病变 (LEL)的诊断、鉴别诊断及其发病机制。方法 :手术切除标本常规石蜡切片和免疫组化ABC法标记。结果 :17例唾腺MALT ML16例为CCL细胞型 ,1例为淋巴浆细胞型 ,具有MALT ML的共同特征 ,免疫组化示单克隆性 ,7例LEL示多克隆性。结论 :Ⅰ级、Ⅱ级LEL为良性病变 ,Ⅲ级为交界性病变。Ⅳ级LEL即MALT ML ,因此唾腺MALT
Purpose To study the diagnosis, differential diagnosis and pathogenesis of salivary mucosa associated lymphoid(MALT ML) tissue type lymphoma and benign lymphoepithelial lesion. Methods Morphologic features were observed in HE staining section and immunohistochemical ABC method was used. Results The morphology of 16/17 cases indicated the type of centrocytic like(CCL)cell and 1 case lymphoplasmacyte. All cases had the same features of MALT ML. B cell monoclonality was identified in 17 cases of MALT ML and polyclonality in 7 cases of LEL. Conclusions Grades Ⅰ and Ⅱ LEL are benign lesions, grade Ⅲ is borderline lesion and grade Ⅳ is MALT ML. Therefore, MALT ML has close relationship with LEL.
出处
《临床与实验病理学杂志》
CAS
CSCD
2000年第6期450-453,共4页
Chinese Journal of Clinical and Experimental Pathology
