摘要
建立了化妆品中姜酮、香兰基丁醚、辣椒素、合成辣椒素4种发热剂的气相色谱串联质谱定性和定量分析方法.在优化的实验条件下,4种发热剂在0.5 ～ 100 mg/L范围内线性关系良好,空白样品在10.0、100.0、500.0 mg/kg 3个加标水平下,回收率为91％ ～ 109％,相对标准偏差为2.1％ ～6.2％.方法的定量下限（S/N=10）：香兰基丁醚、姜酮为5.0 mg/kg;辣椒素、合成辣椒素为10.0 mg/kg.该方法简单、快速、准确,可满足化妆品中4种发热剂的检测要求.
A gas chromatography-tandem mass spectormetry （GC-MS） is developed for the qualitative and quantitative determination of four self-heating compounds in personal care products,including zingerone,vanilly butyl ether,N-vanillylonamide and capsaicin.Under the optimized conditions,the calibration curves of 4 self-heating compounds are linear in the range of 0.5-100 mg/L.The average recoveries of 4 compounds at three spiked levels of 10.0,100,500.0 mg/kg are between 91％-109％,with relative standard deviation of 2.1％-6.2％.The quantitation limits （S/N =10） of zingerone and vanilly butyl ether are 5.0 mg/kg,and those of capsaicin and N-vanillylonamide are 10.0 mg/kg.The method is simple,rapid and accurate,which can meet the requirements of the determination of 4 compounds in personal care products simultaneously.
出处
《现代化工》
CAS
CSCD
北大核心
2014年第3期163-165,共3页
Modern Chemical Industry
基金
国家质检总局科技计划项目(2012QK090)
广州市质监局2014年科技计划项目
关键词
发热剂
气相色谱串联质谱
个人护理产品
self-heating compounds
gas chromatography-tandem mass spectrometry
personal care products
