摘要
目的了解福建省在无脊髓灰质炎后,病毒分离阳性的AFP病例流行特征。方法对2000—2012年病毒分离阳性的AFP病例进行流行病学分析。结果 13年共报告AFP病例1 822例,年均发病率1.70/10万。共采集1 807例标本进行病毒分离,PV阳性4.6%,NPEV阳性11.1%,PV+NPEV混合阳性0.4%,阴性83.9%。PV组中,<1岁占44.6%,流动人口占10.8%,未全程免疫占24.1%,残留麻痹率27.7%,均高于其他组;NPEV组中,<1岁仅占9.5%,流动人口仅占2.5%,未全程免疫仅占9.0%,残留麻痹率仅12.4%。结论在维持无脊灰阶段,需继续提高口服脊灰疫苗(OPV)覆盖率,重点是流动儿童和边远山区儿童。加强NPEV防控亦可减少AFP病例及致残率。
Obejective To analyze epidemiological characteristics of AFP cases with virus positive in Fujian after achieving polio-free. Methods The AFP data was analyzed descriptively from 2000 to 2012. Results Totally 1 822 AFP cases＇ were reported and mean incidence was 1.70/10s during the years. The 1 807 stool specimens Were collected and detected. The isolation rate of vaccine-associated poliovirus （PV） was 4. 6%, of non-poliovirus （NPEV） was 11.1%, of PV mixing with NPEV（PV＋NPEV） was 0.4%, and negative rate was 83.9%. In PV group, 44.6% cases were 〈1 year old, floating population was 10.8%, 24.1% cases didn＇t get full courses vaccination, 27.7% cases were residual paralysis. In NPEV group, 9.5% cases were〈1 years old, floating population was 2.5%, 9.0% cases didn＇t get full courses vaccination, 12.4% cases were residual paralysis only. Conclusions The OPV coverage should be improved and emphasized on the floating children and rural remote areas to maintain the polio-free status. The NPEV control is effective on decreasing AFP and residual paralysis cases.
出处
《海峡预防医学杂志》
CAS
2014年第1期12-14,17,共4页
Strait Journal of Preventive Medicine
基金
福建省自然科学基金资助项目(No.2011J01125)
