摘要
[目的]了解上海市黄浦区2008—2010年沙门氏菌感染的临床特征及发病危险因素。[方法]采用两组1∶1病例对照研究,病例组为2008年1月—2010年6月期间确诊的203名沙门氏菌感染病例。对照组分别来自于医院和社区。采用完全随机抽样的方法,将每月从沙门氏菌感染确诊病例的就诊医院中抽取203例非沙门氏菌感染的腹泻病例作为医院对照组,将每月从沙门氏菌感染确诊病例现住址所在的社区中抽取203例无症状健康者作为社区对照组。对研究对象开展面对面问卷调查,并对数据进行整理和分析。[结果]与医院对照组比较,沙门氏菌感染病例的发热症状较多(OR=2.77,P<0.001),呕吐症状则较少(OR=0.46,P<0.001);与社区对照组比较,一周内可疑饮食史为沙门氏菌感染的主要危险因素(OR=24.01,P<0.001)。[结论]沙门氏菌感染主要因素是不洁饮食,需进一步做好腹泻病的症状监测和病例管理工作,加强对沙门氏菌感染危险因素的控制。
[ Objective ] To determine the clinical symptoms and risk factors of Salmonella infection in residents of Shanghai Huangpu District from 2008 to 2010. [ Methods ] With two 1 ： 1 case-control study designs, 203 patients were diagnosed with Salmonella infection from January 2008 to June 2010, and participants of the two control groups were monthly obtained, by simple random sampling, from the hospitals where the selected Salmonella infection patients had visited （203 hospital controls） and the communities where the selected Salmonella infection patients lived （203 community controls）, respectively. A face-to-face questionnaire survey was conducted. Stata 11.0 was used to perform data cleansing and analysis. [ Results ] Compared to the hospital controls, the Salmonella infection cases had greater chances to have fever （OR=2.77, P〈0.001） and less chances to have vomit （OR=0.46, P 〈 0.001）. Suspicious food history within a week was the main risk factor （OR=24.01, P 〈 0.001） of Salmonella infection with comparison to the community controls. [ Conclusion ] Unhygienic diet largely contributes to Salmonella infection. Surveillance and management of Salmonella infection patients with diarrhea should be enhanced, and the risk factors of Salmonella infection should be further controlled.
出处
《环境与职业医学》
CAS
北大核心
2014年第3期195-198,共4页
Journal of Environmental and Occupational Medicine
基金
中美新发再发传染病合作项目子项目(编号:1U2GG000018-01)
国家十一五重大科技项目(编号:2008ZX 10004-008)
黄浦区科委课题(编号:2010HGG-07)
关键词
沙门氏菌感染
临床症状
危险因素
病例对照
上海
Salmonella infection
clinical symptom
risk factor
case-control
Shanghai
