摘要
目的探讨肺癌患者胸水中VEGF含量的测定及临床意义。方法选择于我院就诊治疗的70例胸水患者,观察两组患者胸水中VEGF含量的差异情况及阳性表达情况和临床病理特征的联系。结果恶性肿瘤患者胸水中VEGF的含量明显高于良性胸水VEGF的含量;胸液中VEGF含量用以诊断恶性胸水的最佳界值为1732.65 pg/ml;恶性胸水中VEGF阳性表达率为86.11%,高于良性胸水26.47%(χ2=25.40,P<0.05);VEGF含量在肺癌的各种临床病理状态下,无显著性差异(P>0.05)。结论肺癌患者胸水中VEGF含量的测定具有一定的临床诊断价值,对良、恶性胸水患者具有鉴别诊断意义。
Objective To explore the significance of VEGF levels in pleural effusion of patients with lung cancer and clinical significance. Methods 70 patients with pleural effusion were selected in our hospital. The difference in VEGF and the positive expression were observed and analyzed. Results The level of VEGF was higher in patients with malignant pleural effusion than benign pleural （P〈0.05）. The best level of VEGF in pleural fluid for the diagnosis of malignant pleural effusion was 1732.65pg/ml. The positive expression rate of VEGF in malignant pleural effusion was 86.11%, which was obviously higher than that in benign pleural effusion （26.47%） （χ2 =25.40, P〈0.05）. There was no significant difference in VEGF among different histological types （P〉0.05）. Conclusion The detection of VEGF in pleural effusion of patients with lung cancer has certain clinical diagnostic value.
出处
《临床肺科杂志》
2014年第4期704-706,共3页
Journal of Clinical Pulmonary Medicine
关键词
VEGF含量
肺癌
胸水
VEGF level
lung cancer
pleural effusion
