摘要
目的：探讨血清尘螨特异性免疫球蛋白E （Ig E ）检测在小儿哮喘诊断与防治的应用。方法该院在2008年2月至2010年4月收治52例小儿哮喘患儿为观察组，＜3岁患儿有11例，3～＜7岁患儿有18例，7～＜12岁患儿有23例；健康儿童44例为对照组，＜3岁患儿有8例，3～＜7岁患儿有16例，7～＜12岁患儿有20例。两组研究对象都进行血清尘螨特异性Ig E检测。结果观察组的血清尘螨特异性IgE浓度为（152．78＆#177;48．95）U/mL ；对照组的血清尘螨特异性IgE浓度为（25．62＆#177;6．49） U/mL ，观察组患儿的血清尘螨特异性IgE浓度明显高于对照组，差异有统计学意义（P＜0．05）。结论小儿哮喘患儿的血清尘螨特异性Ig E阳性率很高，尤其7～＜12岁患儿阳性率最高，所以尘螨过敏原是诱发小儿哮喘的重要因素，通过血清尘螨特异性Ig E检查有助于发现尘螨过敏原，对防治由尘螨过敏原诱发小儿哮喘的重要手段，值得临床推广应用。
Objective To explore the application of serum dust mite specific IgE detection in the diagnosis and treatment of child asthma .Methods 52 children cases of asthma in this hospital from February 2008 to April 2010 were selected as the observation group ,11 cases were ＆lt;3 years old ,18 cases were 3- ＆lt; 7 years old and 23 cases were 7- ＆lt;12 years old ;44 healthy children were taken as the control group ,8 cases were ＆lt;3 years old ,16 cases were 3- ＆lt; 7 years old and 20 cases were 7- ＆lt;12 years old .The two groups were detected the serum dust mite specific Ig E .Results The serum dust mite specific Ig E was （152 .78 ＆#177; 48 .95） U/mL in the observation group and （25 .62 ＆#177; 6 .49） U/mL in the control group ,the serum dust mite specific Ig E concentration in the observation group was significantly higher than that in the control group ,the difference showed the statistical significance （P＆lt;0 .05） .Conclusion The positive rate of serum dust mite specific IgE in child asthma is very high ,especially the children patients of 7- ＆lt;12 years old have the highest positive rate .Therefore ,the dust mite allergen is the important factor inducing child asthma .The detection of serum dust mite specific IgE is conducive to find the dust mite allergen ,which is an important measure for preventing and treating child asthma induced by the dust mite allergen and is worthy of being promoted in clinic .
出处
《国际检验医学杂志》
CAS
2014年第5期555-556,共2页
International Journal of Laboratory Medicine
关键词
哮喘
变应原
螨
免疫球蛋白E
asthma
immunoglobulin E
allergens
mites
