摘要
目的探讨标准化免疫治疗对哮喘儿童屋尘螨特异性Ig G4和肺功能的影响。方法选取本院2012年6月~2013年6月收治的68例哮喘患儿作为研究对象,随机分成实验组和对照组,各34例。实验组给予标准化免疫治疗,对照组给予单纯吸入性糖皮质激素治疗。比较两组的屋尘螨特异性Ig G4及肺功能改善情况。结果实验组的FEV1、PEF水平显著高于对照组,差异有统计学意义（P〈0.05）。实验组治疗后的Ig G4水平显著高于对照组,差异有统计学意义（P〈0.05）。结论标准化免疫治疗对哮喘儿童屋尘螨特异性Ig G4和肺功能具有十分重要的影响,临床应引起足够重视。
Objective To explore the influence of specific immunotherapy on house dust mite specific IgG4 and pul- monary function of asthmatic children. Methods 68 children with asthma from June 2012 to June 2013 in our hospital were selected and randomly divided into the experimental group and the control group,34 cases in each group.The ex- perimental group was given specific immunotherapy,the control group was given inhaled corticosteroids.Then house dust mite specific IgG4 and pulmonary function in two groups was compared. Results The level of FEV1,PEF in the experi- mental group was higher than that in the control group,with significant difference （P〈0.05）.The level of IgG4 after treat- ment in the experimental group was higher than the control group,with significant difference （P〈0.05）. Conclusion Specific immunotherapy has significant impact on house dust mite specific IgG4 and pulmonary function of asthmatic children,and clinical should cause enough attention.
出处
《中国当代医药》
2015年第26期91-93,共3页
China Modern Medicine
基金
广东省深圳市福田区公益性科研项目(TFWS065)
关键词
标准化免疫治疗
儿童
哮喘
屋尘螨特异性Ig
G4
肺功能
Specific immunotherapy
Children
Asthma
House dust mite specific IgG4
Pulmonary function
