摘要
目的研究分析恶性血液病患者医院感染现状及高危因素,为制定预防控制医院感染措施提供依据。方法回顾性分析医院2009年1月-2011年12月恶性血液病住院患者发生医院感染资料,调查感染高危因素并进行分析,采用SPSS2 16.0统计软件对数据进行分析。结果收治的518例恶性血液病患者,发生医院感染171例,感染率33.01%,感染部位以呼吸道为主,占85.38%,检出病原体以革兰阴性菌感染为主,占61.04%;基础疾病中急性白血病感染率最高,占71.92%;高龄、粒细胞缺乏、大剂量化疗是诱发医院感染的主要危险因素。结论恶性血液病患者是医院感染的高发人群,高龄、大剂量化疗是发生医院感染的高危因素,应针对性采取预防控制措施。
OBJECTIVE To observe the prevalence of nosocomial infections in the patients with hematologic malignancies and analyze the high-risk factors so as to put forward measures for prevention and control of the nosocomial infections. METHODS The hematologic malignancies patients with nosocomial infections, who were hospitalized from Jan 2009 to Dec 2011, were enrolled in the study, then the clinical data of the subjects were retrospectively analyzed, the high-risk factors were investigated and analyzed, and the statistical analysis of data was performed with the use of SPSS2 16.0 software. RESULTS Of totally 518 cases of hematologic malignancies, the nosocomial infections occurred in 171 cases with the infection rate of 33. 01 %, among which the cases of respiratory tract infections accounted for 85. 38 %; the cases of infections caused by the gram-negative bacteria accounted for 61. 04%. The incidence of the infections was highest （71. 92%） in the patients with acute leukemia. The advanced age, agranulocytosis, and high-dose chemotherapy were the major risk factors for the nosocomial infections. CONCLUSION The hematologic malignancies patients are the population at high risk of the nosocomial infections; the advanced age and high-dose chemotherapy are the high-risk factors for the nosocomial infections; it is necessary to take targeted prevention measures.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2014年第5期1171-1173,共3页
Chinese Journal of Nosocomiology
基金
绍兴市科技局基金项目(2009A3301)
关键词
医院感染
恶性血液病
预防控制
危险因素
Nosocomial infection
Hematologic malignancies
Prevention and control
Risk factor
