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积雪苷在皮肤科的应用 被引量:6

Application of asiaticoside in dermatology
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摘要 皮肤科临床中应用的积雪苷片及积雪苷霜软膏的主要成分是积雪草总苷。积雪草总苷是积雪草中提取分离出来的三萜皂苷类有效成分。多项临床及动物实验发现,积雪草总苷具有促进创面愈合、防止瘢痕过度增生、抗皮肤老化的作用,且在硬皮病、色素性疾病等方面有一定影响。文献显示,积雪苷在临床应用中具有广泛性及有效性,为此,概述积雪苷在皮肤科中的应用状况。 As one of the active ingredients of the triterpenic fractionof Centella asiatiea, asiaticoside is the main component of Centella triterpenes tablets or cream used at dermatology clinics. Many clinical and animal studieds have revealed that asiaticoside can promote wound healing, prevent excessive scar formation, and counteract skin aging. Moreover, asiaticoside has been widely and efficiently used in the treatment of some diseases, including pigmentary disease and scleroderma, and so on. This paper provides an overview of the application of asiaticoside in dermatology.
出处 《国际皮肤性病学杂志》 2014年第2期138-140,共3页 International Journal of Dermatology and Venereology
基金 上海市科委2010年上海市科技创新计划“积雪苷产品的二次开发”专项资助(10DZl970300).
关键词 积雪草 药物疗法 Centella asiatica Drug therapy
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参考文献15

  • 1Lee JH, Kim HL, Lee MH, et al. Asiaticoside enhances normal human skin cell migration, attachment and growth in vitro wound healing model[J]. Phytomedicine, 2012, 19(13): 1223-1227.
  • 2Kimura Y, Sumiyoshi M, Samukawa K, et al. Facilitating action of asiaticoside at low doses on burn wound repair and its mechanism[J]. Eur J Pharmacol, 2008, 584(2-3): 415-423.
  • 3Tang B, Zhu B, Liang Y, et al. Asiaticoside suppresses collagen expression and TGF-β/Smad signaling through inducing Smad7 and inhibiting TGF-[3RI and TGF-I3RII in keloid fibroblasts [J]. Arch Dermatol Res, 2011,303 (8): 563-572.
  • 4赵亮,方方,王焱,吴信峰,王强,陈晓栋,龚向东,张国成.手术后放疗加口服积雪甙治疗瘢痕疙瘩的临床研究[J].中华皮肤科杂志,2003,36(6):342-344. 被引量:20
  • 5Verrecchia F, Mauviel A. Transforming growth factor-beta signaling through the Smad pathway: role in extracellular matrix gene expression and regulation[J]. J Invest Dermatol, 2002, 118 (2): 211-215.
  • 6Lu L, Ying K, Wei S, et al. Dermal fibroblast-associated gene induction by asiaticoside shown in vitro by DNA microarray analysis[J]. Br J Dermatol, 2004, 151(3): 571-578.
  • 7Lee J, Jung E, Lee H, et al. Evaluation of the effects of a preparation containing asiaticoside on periocular wrinkles of human volunteers[J]. Int J Cosmet Sci, 2008, 30(3): 167-173.
  • 8张洁尘,陈祥生,侯伟,田蔚蔚,陈解春.积雪苷治疗35例鱼尾纹12周疗效观察[J].中华皮肤科杂志,2012,45(1):47-49. 被引量:1
  • 9侯伟,张洁尘,田蔚蔚,张怀亮,陈解春.积雪苷霜软膏治疗黄褐斑随机、双盲、自身对照试验研究[J].中国美容医学,2011,20(5):792-795. 被引量:9
  • 10Suntar I, Akkol EK, Senol FS, et al. Investigating wound healing, tyrosinase inhibitory and antioxidant activities of the ethanol extracts of Salvia cryptantha and Salvia cyanescens using in vivo and in vitro experimental models [J]. J Ethnopharmacol. 2011,135(1):71-7.

二级参考文献23

  • 1刘文阁,秦士德,吴延芳,杨佩瑛,曹艳,黄绿萍.三种方法治疗瘢痕疙瘩的对照观察[J].中华皮肤科杂志,1996,29(4):282-283. 被引量:39
  • 2张涛,荣新洲,杨荣华,利天增,徐盈斌.积雪草苷对增生性瘢痕中转化生长因子-β mRNA及基质金属蛋白酶类表达的影响[J].南方医科大学学报,2006,26(1):67-70. 被引量:35
  • 3吴瑞勤,孙越,韩菁,朱光斗.女性黄褐斑399例临床分析[J].临床皮肤科杂志,2007,36(7):436-436. 被引量:8
  • 4Zhang FL,Wei YJ,Zhu J,et al. Simultaneous quantitation of three major triterpenoid glycosides in Centella asiatica extracts by high performance liquid chromatography with evaporative light scattering detection[J]. Biomed Chromatogr,2008, 22:119-124.
  • 5Zanieri FZ, Assad GB, Campolmi P, et al.Melasma:Successful treatment with pidobenzone 4% (K5 lipogel)[J]. Derrnatolog Thera, 2008,21 : S 18-S19.
  • 6Gupta AK, Gover MD,Nouri K,et al.The treatment of melasma: A review of clinical trials [J].J Am Acad Dermatol,2006, 55 (6): 1048 - 1065.
  • 7Pierard GE. Eemco guidance for the assessment of skin colour[J].J Eur Acad Dermatol Venereol, 1998, 10:1-11.
  • 8Fullerton A, Fischer T,Lahti A,et al.Guidelines for measurement of skincnlour and erythema[J].Contact Dermatitis, 1996, 35 : 1-10.
  • 9Zhang FL,Wei YJ,Zhu J,et al.Simultaneous quantitation of three major triterpenoid glycosides in Centella asiatica extracts by high performance liquid chromatography with evaporative light scattering detection.Biomed Chromatogr,2008,22(2):119-124.
  • 10Lu L,Ying K,Wei S,et al.Dermal fibroblast-associated gene induction by asiaticoside shown in vitro by DNA microarray analysis.Br J Dermatol,2004,151 (3):571-578.

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