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前列腺特异抗原体积密度的测定及其临床意义 被引量:3

The Determination of Prostate PSA Density and Its Clinical Significance
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摘要 目的 通过血清前列腺特异抗原 (PSA)水平、前列腺总体积 ,内外腺体积的测算及PSA体积密度观察 ,探讨血清PSA及前列腺PSA体积密度在前列腺疾病鉴别中的诊断意义。方法 酶联免疫法测血清PSA水平 ,彩色多普勒超声仪ECT端视式探头经直肠测定前列腺的体积。前列腺PSA体积密度的计算 :血清PSA值 /前列腺体积 [单位 :ng/(ml·cm3) ]。结果 二维超声及彩色多普勒超声对良性前列腺增生及前列腺癌的鉴别诊断作用不大 ,血清PSA水平结合前列腺PSA体积密度测定可明显提高前列腺癌的诊断准确率。结论 血清PSA水平升高 。 Objective The aim of this study is to investigate the role of serum prostate specific antigen (PSA) level and the prostate PSA density in the differential diagnosis of different prostate disease,through the observation of serum PSA level,total prostate volume,inner and extra gland volume and prostate PSA density.Methods Serum PSA level was determined by ELISA, while prostate volume was determined by transrectal ultrasound (Color Doppler ultrasound, EC7 probe).Calculation of prostate PSA density:serum PSA/prostate volume.(unit:ug/ml/cc).Results Two dimentional ultrasound and Color Doppler ultrasound have no significant role in the differential diagnosis of prostate carcinoma.Determination of serum PSA level combined with PSA prostate density could obviously increase the accurate rate of diagnosis for prostate carcinoma.Conclusion Increase of serum PSA level and prostate PSA density may be an important basis for the differential diagnosis of benign prostate hyperplasia(BPH) and prostate carcinoma.
出处 《临床超声医学杂志》 2001年第1期10-12,共3页 Journal of Clinical Ultrasound in Medicine
关键词 前列腺癌 前列腺特异性抗原 体积密度 前列腺增生 鉴别诊断 Prostate gland Prostate specific antigen Transrectal ultrasound
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  • 1张文标,中华医学检验杂志,1993年,16卷,166页

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