摘要
目的 了解血清总前列腺特异抗原（ＴＰＳＡ）、游离ＰＳＡ（ＦＰＳＡ）、ＰＳＡ密度（ＰＳＡＤ）在诊断前列腺癌中的作用。 方法 门诊检查４０ 岁以上男性病人ＰＳＡ共３２４ 例，活检筛查出前列腺癌９例（２－８ ％） ，将病人分组进行比较。 结果 前列腺癌组ＴＰＳＡ、ＦＰＳＡ 和ＰＳＡＤ 高于前列腺增生和其他疾病组（ Ｐ＜０－０５） 。血清ＴＰＳＡ＜ ４ｎｇ／ｍｌ、４ ～１０ｎｇ／ｍｌ、＞ １０ｎｇ／ｍｌ 者发现前列腺癌的比例分别为０－５ ％ 、４－１ ％ 、１０－９％ ，三组病人Ｆ／ＴＰＳＡ 以及Ｆ／ＴＰＳＡ≤和＞ ０－１６ 所占比例差异无显著性。 结论 直肠指诊和ＴＰＳＡ 检查是筛查前列腺癌最重要的指标，ＦＰＳＡ、Ｆ／ＴＰＳＡ和ＰＳＡＤ检查有一定的帮助。
Objective To study the role of T PSA,F PSA,F/T PSA and PSAD in the diagnosis of prostate carcinoma. Methods T PSA,F PSA,F/T PSA and PSAD were studied in 324 males over 40 years of age.Biopsy was carried out when needed. Results 9 prostate carcinoma (2.8%) were found out of 324 as verified on biopsy.T PSA,F PSA and PSAD were higher in the carcinoma group ( P <0.05).The incidence of prostate carcinoma with T PSA 4ng/ml,4～10ng/ml and 10ng/ml were 0.5%,4.1% and 10.9% respectively.There was no statistic difference of F/T PSA between the 3 groups and also no statistic difference between F/T PSA under and above 0.16. Conclusions Digital rectal examination and T PSA assay are the most important means to discover prostate carcinoma and F/T PSA and PSAD might be helpful.
出处
《中华泌尿外科杂志》
CAS
CSCD
北大核心
2000年第1期37-40,共4页
Chinese Journal of Urology
