摘要
目的探讨B型脑钠肽(BNP)在慢性阻塞性肺疾病(COPD)中的临床观察。方法选取2011年6月—2013年2月COPD急性发作入我院住院的60例患者,检测60例COPD患者急性发作期血浆BNP值,分析比较发生左心室收缩功能不全组与未发生组BNP水平的区别。结果发生左心室收缩功能不全组BNP水平为(679.6±274.5)pg/ml,未发生组BNP水平为(251.8±134.7)pg/ml,组间比较,差异有统计学意义(P<0.05)。结论BNP对于COPD急性发作期的患者发现左心功能不全有着肯定的作用。
Objective To investigate the clinical efficacy of B - type natriuretic peptide （BNP） in the treatment of chronic obstructive pulmonary disease （COPD）. Methods A total of 60 patients with acute exacerbation of COPD who were admitted to our hospital from June 2011 to February 2013, were selected as study subjects to measure plasma BNP levels. Then the plasma BNP levels of patients with left ventricular systolic dysfunction was compared with the level of patients without left ven- tricular systolic dysfunction. Results The plasma BNP levels of patients with left ventricular systolic dysfunction （ 679. 6 ±274. 5 pg/ml） was higher than the patients＇ without left ventricular systolic dysfunction （251.8± 134. 7 pg/ml）. The differ- ence was statistically significant （P 〈 0. 05）. Conclusion Plasma BNP may be a influence factor of left ventricular systolic dysfunction inpatients with acute exacerbation of COPD.
出处
《临床合理用药杂志》
2014年第6期108-109,共2页
Chinese Journal of Clinical Rational Drug Use
关键词
肺疾病
慢性阻塞性
心室功能障碍
左
B型脑钠肽
Pulmonary disease, chronic obstructive
ventricular dysfunction, left
B - type natriuretic peptide （BNP）
