摘要
目的探讨添加益生菌肠内营养治疗重症急性胰腺炎的临床效果。方法将2012年5月至2013年7月新疆维吾尔自治区人民医院收治的104例重症急性胰腺炎患者分为益生菌肠内营养组(观察组)和常规肠内营养组(对照组),每组52例。比较两组患者住院时间、腹痛消失时间、感染率以及肠内菌群变化情况。结果治疗后观察组与对照组比较,患者腹痛消失时间、平均住院时间均缩短,且感染发生率降低,差异有统计学意义(P<0.05)。观察组患者肠道双歧杆菌、乳杆菌的总数较治疗前显著提高,差异有统计学意义(P<0.05)。结论添加益生菌的肠内营养治疗可有效调节肠道菌群微生态平衡,降低重症急性胰腺炎肠黏膜损伤,保护肠屏障功能。
Objective To investigate the clinical effect of enteral microecopharmaceutics in severe acute pancreatitis （SAP）. Methods A total of 104 patients with SAP enrolled in Xinjiang Uygur Autonomous Region People＇s Hospital from May 2012 to June 2013 were randomly divided into group of enteral microeeopharmaceutics （the observation group） and group of conventional enteral nutrition enteral nutrition （the control group ）, 52 cases in each group. The hospital stays, disappearance time of abdominal pain, infection rate and changes of intestinal flora in the two groups were compared. Results After treatment, disappearance time of abdominal pain and average hospital stays were both shortened between the observation group and the control group with low occurence rate of infection, and the difference between the two groups had statistical significance （P〈0.05）. The amount of intestinal bifidobacterium and lactobacillus in the observation group improved significantly after the treatment with statistically significant difference （P〈0.05）. Conclusion The treatment of adding probioties on enteral nutrition can effectively regulate micro-ecological balance of intestinal flora, reduce intestinal mucosa of SAP and protect the intestinal barrier function.
出处
《现代医药卫生》
2014年第5期664-665,667,共3页
Journal of Modern Medicine & Health
关键词
胰腺炎
肠道营养
治疗结果
益生菌
Pancreatitis
Enteral nutrition
Treatment outcome
Probiotics
