摘要
目的探讨等渗性造影剂碘克沙醇及低渗性造影剂碘海醇对接受冠状动脉造影及介入治疗患者肾功能的影响。方法对第107医院心内科收治肾功能不全患者137例的临床资料进行对比分析。根据使用造影剂的不同分为碘克沙醇组67例和碘海醇组70例。检测其术后24、72 h肾功能,与术前肾功能进行统计学分析。结果两组造影术后72 h肾功能差异有统计学意义(P<0.05);两组患者术后24、72 h血清肌酐变化值差异有统计学意义(P<0.05);两组患者术后24 h肌酐水平差异有统计学意义(P<0.05)。结论与碘海醇相比,碘克沙醇在行冠状动脉造影及介入治疗时对肾功能不全患者影响更小。
Objective To explore the impact of isotonic contrat agent iodixanol and hypotonic one iohexol for coronary angiography on the patients with renal insufficiency undergoing intervention therapy. Methods A total of 137 patients with insufficient renal functions,who underwent CAG or PCI in cardiology department of No. 107 of PLA,were enrolled in the study. According to the used contrast agents 137 cases were divided into iodixanol group （67 cases） and iohexol group （70 cases）. Before surgery,and at 24 hours,72 hours after surgery renal function was detected,then statistical analysis was taken by using SPSS17.0. Results In the incidence of contrast-induced nephropathy 72 h after operation;in the value change at 24 and 72 hours after operation serum creatinine values and 24 hours after operation in creatinine levels between both groups there was statistical difference （P〈0.05,at all）. Conclusion Iodixanol compared with iohexol for coronary angiography and interventional treatment of the patients with renal insufficiency has less impact.
出处
《实用医药杂志》
2014年第2期99-101,共3页
Practical Journal of Medicine & Pharmacy
关键词
碘克沙醇
碘海醇
冠脉造影
介入治疗
Iodixanol
Iohexol
Coronary angiography
Intervention therapy
