摘要
目的探讨参芎葡萄糖注射液联合水化治疗对造影剂肾病的防治作用。方法选取自2014年6月—2016年6月收集的拟行冠脉造影的患者80例作为研究对象,将其随机分为对照组和试验组,每组各40例。对照组给予水化治疗,试验组在水化治疗的基础上采用参芎葡萄糖静脉滴注治疗。对比两组患者术前及术后48 h血肌酐水平、肌酐清除率及造影剂肾病发生率。结果术后试验组患者血肌酐水平低于对照组,肌酐清除率高于对照组,造影剂肾病发生率低于对照组,差异均具有统计意义(P<0.05)。结论参芎葡萄糖联合水化治疗可减轻造影剂肾损害,降低造影剂肾病发生率。
Objective To investigate the prevention of contrast-induced nephropathy with Shenxiong glucose combined with hydration therapy. Methods A total of 80 patients who underwent coronary angiography in our hospital from June 2014 to June 2016 were randomly divided into control group and experimental group, a total of 40 cases in each group. The patients in control group were administrated hydration therapy. The patients in treatment group were administrated Shenxiong glucose and combined with hydration. The levels of serum creatinine, creatinine clearance rate and the incidence of contrast induced nephropathy were compared before and after operation for 48 h in two groups. ResultsCompared with control group, the serum creatinine level of the treatment group was lower, and the creatinine clearance rate was higher. The incidence of contrast induced nephropathy was lower than that of the control group, and the difference was statistically significant（P〈0.05）. Conclusion Shenxiong glucose combined with hydration therapy can reduce the renal damage of contrast medium, and reduce the incidence of contrast induced nephropathy.
作者
李在楠
王彩虹
杨斌
LI Zainan WANG Caihong YANG Bin(Department of Nephrology, Chifeng Hospital Chifeng Inner Mongolia 024000, China Department of Cardiology)
出处
《中国继续医学教育》
2017年第3期178-179,共2页
China Continuing Medical Education
关键词
造影剂肾病
参芎葡萄糖
水化治疗
contrast-induced nephropathy
Shenxiong glucose
hydration therapy
