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空肠弯曲杆菌生物学特性及分型技术研究新进展 被引量:7

New Research Progress on Campylobacter jejuni Typing and its Biological Characteristics
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摘要 空肠弯曲杆菌是引起人类弯曲杆菌病的主要致病菌,也是主要食源性致病菌之一。该菌主要引起人类腹泻,还可造成心内膜炎、关节炎、菌血症等全身性疾病,最严重的并发症是引发格林—巴利综合征。空肠弯曲杆菌在发达国家的感染率甚至有超过沙门氏菌而居首位的趋势。有报道将空肠弯曲杆菌称为"下一个沙门氏菌",使得世界各国对该菌高度重视。对空肠弯曲杆菌进行生物学特性分析和分型研究,不仅对其鉴定、监测和制定防控措施起到重要作用,且可帮助了解其致病和耐药机制。作者对空肠弯曲杆菌的生物学特性、血清学分型和基因分型3个方面的最新进展进行了综述和分析。 Campylobacter jejuni (C. jejuni) is a major pathogen of human campylobacteriosis, as well as one of the major food-borne pathogen. It can not only cause human diarrhea, but also cause many systemic diseases such as endocarditis, arthri- tis, septisis. The most serious complication it can cause is the Guillain Barre syndrome. In developed countries, C. jejuni even has a trend to excess Salmonella and be reported as next Salmonella, which has caused a worldwide concern. Analysis of bio- logical characteristics for C. jejuni can help us to distinguish it with other pathogens. Typing methods play important roles in the identification, monitoring and prevention of C. jejuni. It can also help us to understand its virulence and resistance mecha- nisms to C. jejuni. This paper reviews advances of C. jejuni in biological characteristics, serotyping and genotyping methods so as to help us further understand its new progress in these areas.
出处 《中国畜牧兽医》 CAS 北大核心 2014年第2期223-228,共6页 China Animal Husbandry & Veterinary Medicine
关键词 空肠弯曲杆菌 生物学特性 分型方法 Campylobacter jejuni biological characteristics typing methods
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