摘要
目的 探讨膜式液基薄层细胞学检查（TCT）和人乳头状瘤病毒（HPV）检测在宫颈癌筛查中的临床意义.方法 选取2011年1月至2013年6月门诊就诊的2000例有性生活史并自愿进行宫颈癌筛查的患者,分别进行病理检查、TCT和HPV检测.以病理检查结果为金标准,比较TCT和HPV检测对宫颈癌前病变及宫颈癌的检出符合率.结果 病理检查结果阳性的357例患者,TCT检出符合率为86.6％（309/357）,HPV检测检出符合率为91.0％（325/357）,两种方法检出符合率比较差异无统计学意义（P＞0.05）;TCT联合HPV检测的检出符合率为100％.结论 TCT联合HPV检测有助于提高宫颈癌的检出率,早期发现癌前病变,降低病死率,具有良好的临床价值和社会价值.
Objective To investigate the clinical value of membrane thin prep cytology （TCT） and human papilloma virus （HPV） testing for the screening of cervical cancer.Methods Two thousand voluntary outpatients with sexual life history screened for cervical cancer in our hospital from January 2011 to June 2013 were received pathological examination,TCT and HPV testing.With pathological findings as the gold standard,the coincidence detection rates of two methods for cervical precancerous lesions and cervical cancer were compared.Results Pathological examination of 357 patients were positive,the coincidence detection rate of TCT was 86.6％ （309/357）.The coincidence detection rate of HPV testing was 91.0％ （325/357）.Coincidence detection rate of two methods had no statistical significant difference （P ＞ 0.05）.Coincidence detection rate of TCT combined with HPV testing was 100％.Conclusion TCT combined with HPV testing can significantly improve the detection rate of cervical cancer.It can early detect precancerous lesions and reduce mortality with good clinical and social value.
出处
《国际医药卫生导报》
2014年第3期374-376,共3页
International Medicine and Health Guidance News
关键词
TCT
HPV检测
癌前病变
宫颈癌
TCT
HPV testing
Precancerous lesions
Cervical cancer
