摘要
目的对比TCT（ThinPrep Cytology Test）和TCT联合HPV—DNA（human papillomavirus）在高危妇女子宫颈病变筛查中的价值。方法对有高危因素的妇女进行普查，分为TCT检测组及TCT联合HPV—DNA检测组，只要有异常都考虑为阳性。同时进行阴道镜下活检，以病理结果为金标准。比较两种方法的检山漏诊率。结果TCT筛查组筛查小阳性病例38例，病理组织学最后确诊病例32例，其中TCT假阳性14例，漏诊8例，漏诊率为25％；TCT联合HPV—DNA筛查组筛查出阳性病例42例，病理组织学最后确诊病例38例，其中假阳性6例，漏诊2例，漏诊率为5％，两组漏诊率相比，差异有极显著性（P〈0．01）。结论对于宫颈癌及其癌前病变的筛查及早期诊断，应以宫颈细胞学检查和高危HPV检测相互结合以提高检出率，降低漏诊率。
Objectve To evaluate the methods of the screening of cervical cancer and precancerous lesions in risk factor women.Methods 100 women with risk factor were given TCT , 100 women with risk factor were givenTCT and HPV-DNA , all women were given cytology exam inations.Pathology was golden standard for the diagnoses of different methods.Results TCT examed the rate of missed diagnosis is 25%, TCT and HPV-DNA examed the rate of miss diagnosis is 5%, between two methods were significant（ P〈 0.01 ）. Conclusion TCT and HPV-DNA exam could improve detective rate in the screening of cervieal cancer and precancerous lesions.
出处
《国际医药卫生导报》
2010年第7期810-812,共3页
International Medicine and Health Guidance News
