摘要
文冠木正丁醇提取物对二甲苯致小鼠耳肿胀、蛋清致大鼠足肿胀、角叉菜胶致小鼠足肿胀、醋酸致小鼠腹腔毛细血管通透性增加、小鼠羧甲基纤维素囊中白细胞游走、小鼠棉球肉芽肿生长均有显著的抑制作用 ,同样剂量下 ,文冠木正丁醇提取物对角叉菜胶致去双侧肾上腺小鼠足肿胀仍有显著的抑制作用 。
The anti inflammatory effect of n butanol extract of Xanthoceras sorbifolia Bunge(BEX)was studied in this paper.The ear edema resulted from dimethyl benzene,paw edema induced by carrageenin,the increase of vascular permeability caused by acetic acid,the chemotaxis of WBC induced by CMC and the weight of cotton granuloma in mice and hind paw edema induced by fresh egg white in rats were inhibited significantly by ig BEX daily for 7 days,respectively.The carrageenin induced paw edema was also inhibited markedly in adrenal ectomiced mice.No changes in weight of adrenal and the concentration of vitamin C were observed,indicating that the anti inflammatory effect of BEX was not related to pituitary adrenal system.
出处
《沈阳药科大学学报》
CAS
CSCD
2001年第1期53-56,共4页
Journal of Shenyang Pharmaceutical University
关键词
文冠木正丁醇提取物
抗炎作用
去肾上腺小鼠
n-butanol extract of Xanthoceras sorbifolia Bunge
anti-inflammation
adrenal-ectomiced mice
