摘要
目的评价白芍总苷联合曲安奈德局部注射治疗口腔扁平苔藓的临床疗效。方法 58例口腔黏膜扁平苔藓患者随机分为治疗组和对照组,分别采用白芍总苷联合曲安奈德局部注射及单独曲安奈德局部注射治疗,同时记录VAS和REU分值,分别在治疗1、3、6个月时评定疗效。结果 1个月时治疗组疗效为82.7%,对照组为79.3%,2组疗效差异无统计学意义(χ2=0.112,P>0.01),3个月时治疗组疗效为86.2%,对照组为51.7%,2组差异有统计学意义(χ2=15.241,P<0.01),6个月时治疗组为79.3%,对照组为37.9%,2组差异有统计学意义(χ2=34.621,P<0.01)。结论白芍总苷联合曲安奈德局部注射治疗口腔扁平苔藓可提高临床疗效,优于单独使用曲安奈德局部注射。
Objective To observe the efficacy and safety of total glucosides of paeony combined with intralesional triamcinolone acetonide injection for oral lichen planus. Methods 58 patients with clinically confirmed erosive and ulcerative OLP were randomly divided into two groups, treated with TGP ＋ TA and TA separately,meanwhile the VAS and REU scoring system was utilized to compare the signs and symptoms. Results There were no statistically significant difference in effective rate between the treatment group and control group（ X^2 = 0.112,P 〉 0.01 ）at the first month, yet there was significant difference in effective rate between the treatment group and control group （ X^2 = 15.241, P 〈 0.01 ） at the third month, and so did at the sixth month （ X^2 = 34.621, P 〈 0.01 ）. Conclusions Total glucosides of paeony combined with intralesional triamcinolone acetonide injection can significantly enhance the effect safely in the treatment of OLP.
出处
《口腔医学》
CAS
2014年第1期56-58,共3页
Stomatology
关键词
白芍总苷
曲安奈德
口腔扁平苔藓
total glucosides of paeony
triamcinolone acetonide
oral lichen planus
