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药物干预对胆囊结石体外震波碎石治疗后的抗复发临床观察 被引量:1

Clinical observation of the effect of drugs admission on anti-recurrence of gallstones afterer ESWL
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摘要 目的 :临床观察药物干预抗胆囊结石复发疗效。方法 :通过对经体外震波碎石后结石消失病人16 3例 2年 9个月~ 7年 7个月的随访观察。对不同服药组间复发率进行比较。结果 :多发结石和单发结石的复发率分别为 6 4%和 2 8.4% (χ2值 =2 0 .71,P<0 .0 1)。结石消失后 1、2、3、4、5、6、7年内逐年复发率分别为14.7%、2 3.7%、33.1%、36 .2 %、40 .5 %、44 .2 %和 44 .8%。熊去氧胆酸组结石复发率为 2 6 .7% ,复发率最低。结论 :在结石消失后间断较长时间 (4年 ) Objective:To observe the effect of drugs on anti recurrence of gallstones.Methods:163 subjects who had no residual gallstones after ESWL were involved in the trial. They were followed up from 31 to 91 months. The recurrence rate was compared between different groups.Results:The recurrence rate of multiple gallstones group(64%) is higher than that of single one. The recurrence rate of gallstone among all subjects increases yearly from 14.7%,23.7%,33.1%,36.2%,40.5% and 44.2% to 44.80%. respectively,after gallstones disappeared.Subjects who had received lower dose UDCA(ursodeoxycholic acid) intermittently recurred in lowest frequency.Conclusion:It may be a usable regimen in anti recurrence of gallstones that UDCA is administered in a lower dose.
作者 汪裕 王炳生
出处 《肝胆胰外科杂志》 CAS 2000年第4期187-188,共2页 Journal of Hepatopancreatobiliary Surgery
关键词 胆囊结石 药物干预 熊去氧胆酸 体外震波碎石 gallstones anti-recurrence drugs admission ursodeoxycholic acD
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