摘要
探讨体外冲击波碎石术(ESWL)后胆囊结石复发的危险因素。方法:对454例经ESWL治疗后结石已消失的病人进行多因素分析。对85例病人检测血清胰岛素和总胆汁酸值。结果:经1～8.8年随访,胆囊结石的复发率分别为,1年11.9％,2年20.2％,3年23.1％,4年34.8％,5年35.7％和5年以上37.2％。胆囊结石复发的危险因素包括:(1)有胆囊结石的家属史(P<0.05);(2)患者肥胖(P<0.05);(3)胆囊壁增厚(P<0.01);(4)血清胰岛素平均值较低(P<0.05);(5)血清总胆汁酸平均值较高(P<0.05)。结论:有胆囊结石家属史、患者肥胖、胆囊壁增厚及血清胰岛素相对不足等均为促使胆囊结石复发的危险因素,对ESWL的治疗对象应予更严格地挑选。
To investigate the risk factors of cholecystolithiasis recurrence after ESWL. Methods: A multifactorial analysis was performed for 454 patients with gallbladder stones after ESWL therapy. The serum level of insulin and total bile acid were determined in 85 patients. Results: After 1~8.8 years of follow-up, the 1,2,3,4,5 and over 5 years recurrence rate of gallbladder stones was 11.9%, 20.2%, 23.1%, 34.8%, 35.7% and 37.2% respectively. The risk factors of cholecystolithiasis recurrence were found to be: (1) familial history of cholecystolithiasis (P<0.05); (2) obesity (P<0.05); (3) thicke-ning of the gallbladder wall (P<0.01); (4) low mean value of serum insulin (P<0.05); (5) high mean va-lue of total bile acid (P<0.05). Conclusions: Familial history of cholecystolithiasis, obesity, thickening of the gallbladder wall and relative lowering of serum insulin increase the risk of cholecystolithiasis recurrence after ESWL. Candidates for ESWL should be strictly selected.
出处
《外科理论与实践》
1999年第1期33-35,共3页
Journal of Surgery Concepts & Practice
关键词
胆结石
体外碎石
冲击波碎石术
复发
危险因素
Cholecystolithiasis Extracorporeal shock wave lithotripsy Recurrence Risk factors
