摘要
四唑和噻二唑类衍生物具有广泛的生物活性,如抗真菌、抗霉菌、抗肿瘤、抗结核菌,以及促进植物生长等活性,1,4-二取代酰氨基硫脲是合成此类物质的重要原料,为了深入研究同一分子中聚结各种杂环化合物的合成及生物活性,我们将1-[5-(3-吡啶)-四唑-2-乙酰基]-4-芳氨基硫脲(1)进行环化脱水制得5-[5-(3-吡啶)-四唑-2-亚甲基]-2-芳氨基-1,3,4-噻二唑2_(a-i)新化合物。
Syntheses of ten 5-[5-(3-pyridyl)-2H-tetrazol-2-yImethylene]-2-arylamino-1 ,3,4-thiadi-azoles(2,-i) were described with a view to studying their biological properties. The structures of these compounds were characterized by eleme nalysis,IR,1H NMR and MS.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
1991年第8期1069-1071,共3页
Chemical Journal of Chinese Universities
关键词
酰氨基硫脲
杂环衍生物
四唑
噻唑
Heterocycle, Acylthiosen rbazides, 1,3,4-Thiadiazoles
