摘要
本文报道21种新的1-芳酰基-4[4′-2,2,6,6-四甲基哌啶)-1-氧]-氨基硫脲化合物(5_(a-u)的合成,利用IR、MS和ESR谱确认了产品结构,讨论了IR、MS、ESR谱的性质,初步观察了5_(a-u)对L_(7712)白血病细胞的抑制作用。
Twenty one 1-arylformyl- 4-[4'- (2, 2, 6, 6-tetramethyl-piperidine)-1-oxy] thiosemicar-bazides were synthesized. Their structures were ascertained. And the characters of IR, MS and ESR spectra were discussed. The results of the preliminary experiment show that compounds(S) possess an inhibiting activity on L7712-Lekemia cell.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
1991年第8期1056-1060,共5页
Chemical Journal of Chinese Universities
关键词
酰氨基硫脲
杂环衍生物
抗癌活性
Acylthiosemicarbazides, Piperidine nitroxide, Anticancer activity
