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中国健康人血清胆固醇酯转运蛋白水平 被引量:8

Serum Cholesteryl Ester Transfer Protein Levels in Healthy Chinese Subjects
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摘要 为研究中国健康人血清胆固醇酯转运蛋白水平和分布特征 ,采用“Sandwich”酶免疫法测定了 112 8例健康人群血清胆固醇酯转运蛋白水平 ,结果为 1.84± 1.5 5mg/L ,胆固醇酯转运蛋白水平倾向于低浓度的偏态分布 ,女性胆固醇酯转运蛋白水平明显高于男性 (分别为 2 .40± 1.6 5mg/L和 1.49± 1.37mg/L ,P <0 .0 0 1)。胆固醇酯转运蛋白水平与年龄之间呈显著的负相关 (r=- 0 .19,P <0 .0 0 1) ,与其他各项血脂浓度间均无相关性。 Aim To determine the serum CETP concentration in 1 128 healthy Chinese subjects, and to analyze the characteristics of CETP level and distribution in different age and sex groups. Methods The CETP concentration was determined using “Sandwich” ELISA. Results The CETP level was 1.84±1.55 mg/L. The frequency distribution of CETP in healthy subjects was markedly skewed to low concentration. The frequency distribution of CETP in female was significantly higher than that in male (2.40±1.65 mg/L vs. 1.49±1.37 mg/L,P<0.001). There was a highly inverse correlation between the CETP level and age (r=-0.19,P<0.001), while no relation was found between CETP level and lipids concentration. Conclusion The regular pattern of serum CETP in 1 128 healthy Chinese subjects has been demonstrated.
出处 《中国动脉硬化杂志》 CAS CSCD 2000年第4期289-291,共3页 Chinese Journal of Arteriosclerosis
基金 军队九五科研基金课题(1996D025)
关键词 胆固醇酯 转运蛋白 人群 参考值 血脂 动脉粥样硬化 Cholesteryl Ester Carrier Proteins Population Reference Values Lipids Atherosclerosis
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