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尿多酸肽抗肿瘤作用的研究进展

Research progress of uroacitide on the antitumor effect
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摘要 尿多酸肽(CDA-2)是健康男性尿液经酸化、树脂吸附、乙醇洗脱、真空干燥等得到的混合物,含有多种有机酸和多肽成分,主要包括苯乙酸、吲哚乙酸、马尿酸、苯乙酰谷氨酰胺和小分子多肽等细胞分化诱导剂、分化帮助剂和抗恶病质剂。通过多种成分的共同作用,发挥抗癌效果,是全新的非细胞毒性抗肿瘤物,其作用靶点是抑制甲基转移复合酶,使癌细胞达到最终分化,对多种肿瘤细胞有明显的抑制生长及诱导分化作用。
出处 《湖南中医药大学学报》 CAS 2013年第10期107-108,共2页 Journal of Hunan University of Chinese Medicine
关键词 尿多酸肽 甲基转移复合酶 诱导分化 综述文献 Uroacitide Methyltransferase composite enzyme Inducing differentiation
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